Stuart Orkin, MD, David G Nathan Professor of Pediatrics, Harvard Medical School; Chair, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston Childrens Hospital; Investigator, Howard Hughes Medical Institute, Boston, MassachusettsDavid Nathan, MD, President Emeritus, Dana-Farber Cancer Institute, Physician-in-Chief Emeritus, Boston Childrens Hospital; Stranahan Distinguished Professor of Pediatrics and Professor of Medicine, Harvard Medical School, Boston, MassachusettsDavid Ginsburg, MD, James V Neel Distinguished University Professor, Departments of Internal Medicine, Pediatrics, and Communicable Diseases, and Human Genetics, Investigator, Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MichiganA. Thomas Look, MD, Professor of Pediatrics, Harvard Medical School; Vice Chair for Research, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston Childrens Hospital, Boston, MassachusettsDavid Fisher, MD, PhD, Chief, Department of Dermatology, Director, Cutaneous Biology Research Center, Massachusetts General Hospital; Director, Melanoma Program, Massachusetts General Hospital Cancer Center, Boston, MassachusettsSamuel Lux, MD, Robert A Stranahan Professor of Pediatrics, Harvard Medical School; Chief Emeritus, Hematology/Oncology, Boston Childrens Hospital, Boston, Massachusetts